Chembiochem : a European journal of chemical biologyAdamantaneHumansThioureaDrug DesignAnti-Allergic Agents
Design, Synthesis, and Bioevaluation of Adamantane-1-Carboxamide N-Acylthioureas for Airway Antiallergic Therapy.
Rahime Eshaghi Malekshah, Amir Karim, Chi-Xin Guo, Yu-Ting Chu, Feng-Ming Yang, Sung-Po Hsu, Sodio C N Hsu
Published: 202610.1002/cbic.202500756
Abstract
Airway epithelial cells (AECs) serve as the first line of defense against environmental pollutants, with exposure to traffic-related particles known to exacerbate allergic asthma. In this study, a series of adamantane-containing N-acylthiourea compou…
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