Chembiochem : a European journal of chemical biologybcl-X ProteinApoptosisHumansRecombinant Proteinsbcl-2-Associated X Protein
Characterization of the Direct and Indirect Inhibition of Apoptosis by Full-Length Recombinant Bcl-xL Monomers.
Christina Elsner, Ludovica M Epasto, Adeline Cieren, Dominik Gendreizig, Svetlana Kucher, Daniel Roderer, Enrica Bordignon
Published: 202610.1002/cbic.202500683
Abstract
The Bcl-2 protein Bcl-xL is an inhibitor of intrinsic apoptosis which either directly inhibits the pore-forming Bcl-2 proteins, like Bax or Bak, or indirectly inhibits pore formation by sequestering the pro-apoptotic BH3-only activators. The structur…
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