Chembiochem : a European journal of chemical biologyHumansAmyloidPrionsAmyloidogenic ProteinsAnimals
Amyloid-Inducing Agents via Metabolite Self-Assembly Expands the Boundary of Prion Concept beyond Proteins.
Kailash Prasad Prajapati, Shikha Mittal, Masihuzzaman Ansari, Bibin Gnanadhason Anand, Karunakar Kar
Published: 202610.1002/cbic.202500492
Abstract
The prion concept fundamentally signifies the intrinsic cross-seeding potential of misfolded protein-generated amyloid entities to efficiently induce amyloid aggregation in normally folded proteins leading to formation of cytotoxic amyloid structures…
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