Chemistry & biodiversityAlzheimer DiseaseChelating AgentsGenisteinDrug DesignHumans
Novel Biochanin A Carbamate Derivatives as Multifunctional Anti-Alzheimer's Disease Metal Chelators: Design, Synthesis, and Activity Evaluation.
Yiyi Sun, Xinjie Jiang, Xiaoyue Yi, Caiyun Wang, Xiangyu Zhang, Rui Shen, Aihong Yang, Xiaodi Kou
Published: 202510.1002/cbdv.202501827
Abstract
Considerable evidence suggests that metal ions play crucial roles in Alzheimer's disease (AD) progression, spurring the development of metal-involved therapeutic strategies. In this study, biochanin A, a bioactive ingredient derived fromTrifolium pra…
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