Chemistry & biodiversityHumansAbietanesAntineoplastic AgentsDrug DesignDrug Screening Assays
Design, Synthesis and Antitumor Evaluation of Novel Dehydroabietic Acid Derivatives Bearing an α,β-Unsaturated Ketone Moiety.
Zihan Fan, Xinyu Zhao, Meishan Li, Hengshan Wang, Rizhen Huang
Published: 202510.1002/cbdv.202501583
Abstract
A series of dehydroabietic acid (DHAA) derivatives containing α,β-unsaturated ketone moieties were designed, synthesized and evaluated as anticancer agents. The inhibitory activities of target compounds against SW480, HepG2, MDA-MB-231 human cancer c…
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