Biotechnology progress
Enhanced lentiviral vector recovery and separation using arginine hydrochloride with CIM QA monoliths.
Andrew J Kocot, Shivani Kulkarni, Ronit Ghosh, Scott H Altern, Jonathan S Dordick, Todd M Przybycien, Steven M Cramer
Published: 202610.1002/btpr.70102
Abstract
Lentiviral vectors (LVVs) offer distinct advantages including large payload capacity and stable transduction of non-dividing cells, making them well-suited for ex vivo modification of stem or immune cells. However, chromatographic purification of LVV…
Preview only. Read the full abstract at the source