Biomedical chromatography : BMCAnimalsTandem Mass SpectrometryRatsChromatographyHigh Pressure Liquid
Simultaneous Determination of Thioridazine and Its Metabolites by UHPLC-MS/MS With Application to a Pharmacokinetic Study in Rats.
Kyung-Sun Moon, Jong-Min Song, Sung-Hoon Ahn
Published: 202610.1002/bmc.70298
Abstract
To develop an LC-MS/MS method for simultaneous quantification of thioridazine and its metabolites in rat plasma, samples were prepared by protein precipitation and filtration using thioridazine-d3 as an internal standard. Chromatographic separation w…
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