Biomedical chromatography : BMCDrug MonitoringHumansCritical IllnessReproducibility of ResultsChromatography
Establishing Plasma Concentration Methodology for Trimethoprim/Sulfamethoxazole: Application in Therapeutic Drug Monitoring of Critically Ill Patients.
Xiangxiang Fu, Jiao Fu, Haibiao Gong, Lili Zhong, FangLing Wang, MengYu Mei, Bingli Zhang, Wenya Xu, Xian Zhang, Min Wang, Wanyang Sun, Lei Yang
Published: 202510.1002/bmc.70235
Abstract
This study aimed to develop a high-throughput and high-sensitivity method for simultaneously determining trimethoprim (TMP), sulfamethoxazole (SMX), and its metabolite acetyl-N-sulfamethoxazole (NSMX) in critically ill patients' plasma. The samples w…
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