Biotechnology journalCHO CellsCricetulusAnimalsTransfectionAntibodies
Leveraging Transfection Dose Streamlines the Establishment of a Chinese Hamster Ovary Cell Targeted Integration System.
Tao Sun, Xin Zhou, Yu Zhang, Nan Yan, Ding Huang, Kee Wee Tan, Sam Zhang, Hang Zhou, Fei Chen, Xiaoyue Chen
Published: 202510.1002/biot.70165
Abstract
Targeted integration (TI) expression system has emerged as an alternative to random integration in cell line development (CLD) involved in biologics development and manufacturing. A key element of a robust TI CLD system is the construction of a high-…
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