BioFactors (Oxford, England)DiterpenesHumansFerroptosisPancreatic NeoplasmsHSP90 Heat-Shock Proteins
Andrographolide Promotes Ferroptosis in Pancreatic Cancer via Targeting and Activating HSP90/GPX4 Ubiquitination.
Asmat Ullah, Hongyan Xing, Xinxin Wang, Chuanzan Zhou, Zhang Rui, Haroon Iqbal, Xie Chengfeng, Zaheer Ullah Khan, Naveed Ullah Khan, Zhi Min Jin
Published: 202510.1002/biof.70063
Abstract
Pancreatic adenocarcinoma accounts for 90% of pancreatic cancer cases, the deadliest kind. PC patients' poor immunotherapy, chemotherapy, and other responses lead to a generally failed treatment strategy. Thus, understanding molecular processes is es…
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