Biometrical journal. Biometrische ZeitschriftHumansRandomized Controlled Trials as TopicNeoplasmsBayes TheoremTreatment Outcome
Evaluating Causal Effects on Time-to-Event Outcomes in an RCT in Oncology With Treatment Discontinuation.
Veronica Ballerini, Björn Bornkamp, Fabrizia Mealli, Craig Wang, Yufen Zhang, Alessandra Mattei
Published: 202510.1002/bimj.70092
Abstract
In clinical trials, patients may discontinue treatments prematurely, breaking the initial randomization. In our motivating study, a randomized controlled trial in oncology, patients assigned the investigational treatment may discontinue it due to adv…
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