Biotechnology and applied biochemistry
Lipase-Catalyzed Promiscuous Reaction for the Synthesis of Pyrido[2,3-d]pyrimidine Scaffolds via One Pot Knoevenagel-Michael-Aromatization in Aqueous Ethanol.
Pratik P Wagh, Kiran S Dalal, Suraj P Vasave, Yogesh B Wagh, Bhushan L Chaudhari, Dipak S Dalal
Published: 202510.1002/bab.70057
Abstract
Porcine pancreas lipase (PPL) has been used as an efficient green biocatalyst for the multicomponent synthesis of pyrido[2,3-d]pyrimidine derivatives and expanding the biocatalytic promiscuity of lipase in organic synthesis. This robust procedure inv…
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