Arthritis & rheumatology (Hoboken, N.J.)
In synergy with interferon-gamma, interleukin-17 activates vascular stromal cells towards a pro-inflammatory profile in giant cell arteritis.
Hélène Greigert, André Ramon, Claudie Cladiere, Baptiste Lamarthée, Corentin Richard, Marion Ciudad, Alexis Varin, Noémie Herrmann, Roman Praliaud, Guillaume Brenac, Jérôme Razanamahery, Louis Arnould, Pierre-Henry Gabrielle, Catherine Creuzot-Garcher, Georges Tarris
Published: 202610.1002/art.70051
Abstract
OBJECTIVES: This study investigated the role of IL-17 in Giant Cell Arteritis (GCA), which has remained uncertain despite previous research suggesting a contribution of Th17 cells to the disease. METHODS: Temporal artery biopsies (TABs) were cultured…
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