Arthritis & rheumatology (Hoboken, N.J.)
DNA methylation profiling reveals distinct epigenetic clusters and suggests epigenetic patterns associated with sex and disease activity in childhood-onset lupus.
Desiré Casares-Marfil, Gülşah Kavrul Kayaalp, Vafa Guliyeva, Özlem Akgün, Şeyma Türkmen, Elif Kılıç Könte, Seher Şener, Sezgin Şahin, Özgür Kasapçopur, Betül Sözeri, Selçuk Sözer Tokdemir, Seza Özen, Nuray Aktay Ayaz, Amr H Sawalha
Published: 202510.1002/art.70045
Abstract
OBJECTIVES: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organs, with childhood-onset SLE (cSLE) typically presenting a more severe course and greater genetic risk than adult-onset SLE. While DNA methylation p…
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