Arthritis & rheumatology (Hoboken, N.J.)
Single-Cell Profiling Reveals Divergent Mechanisms of Fibrosis in Localized Scleroderma and Systemic Sclerosis.
Junxia Huang, Xue Han, Xiuyuan Wang, Liuting Huang, Manna Lin, Cheng Chen, Linzhu Kang, Yuqing Huang, Feifei Hu, Xinzhi Xu, Xue Yang, Ji Yang
Published: 202510.1002/art.70039
Abstract
OBJECTIVES: Localized scleroderma (LoS) and systemic sclerosis (SSc) are both fibrotic diseases, but LoS is limited to the skin, whereas SSc involves systemic organ fibrosis. This study aimed to elucidate the mechanisms underlying these differences.…
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