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Retrospection of the USFDA-Approved Halogenated Drugs and Their Implication in Medicinal Chemistry and Drug Discovery: A Perspective of Approved Drugs Between 2019 and 2024.
Nemat Ali, Fahad T Alotaibi, M Arockia Babu, Thakur Gurjeet Singh, Ali M Alaseem, Yogita Tyagi, Nisha Bansal
Published: 202610.1002/ardp.70190
Abstract
Halogens are utilized in drug discovery and development due to their ability to precisely tune the molecular properties of drug candidates. The halogen substituents play a crucial role in determining the stability, lipophilicity, and receptor binding…
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