Archiv der PharmazieHumansErbB ReceptorsAntineoplastic AgentsPyrimidinesDrug Design
Design, Synthesis, Biological Evaluation, and In Silico Studies of Novel Furo[2,3-d]pyrimidine Derivatives as EGFR Inhibitors With Potential Antitumor Activity.
Samar I Faggal, Walid E Elgammal, Amr Sonousi, Amr M Abdou, Soha O Hassanin, Rasha A Hassan
Published: 202510.1002/ardp.70146
Abstract
In the pursuit of developing targeted therapies, novel furo[2,3-d]pyrimidine compounds were synthesized, incorporating the characteristic structural features of EGFR tyrosine kinase inhibitors. These compounds were screened for antiproliferative effe…
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