Archiv der PharmazieAnimalsPsoriasisNuclear Receptor Subfamily 1Group FMember 3
Ergosterol, a Novel RORγt Inverse Agonist, Enhances Skin Barrier Function and Reduces Skin Inflammation in IMQ-Induced Mice With Psoriasis.
Ling Jiang, Jiangming Zhong, Huixiong Chen, Yi Li, Qi Zhou, Miaohong Yang, Li Lin, Peng Shu, Zhiyun Du
Published: 202510.1002/ardp.70121
Abstract
Retinoic acid receptor-related orphan receptor gamma-t (RORγt) is one of the nuclear receptor transcription factors that plays a key role in the differentiation of pro-inflammatory IL-17+ T helper cells. Recently, RORγt has attracted increasing atten…
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