Angewandte Chemie (International ed. in English)
Pyroglutamate PTMs as Bioorthogonal Reactive Handles: Ru/Ni Photoredox Coupling.
Reyner D Vargas, Baorui Xiang, Yuecheng Jiang, Carlos D Llanos, Laura Segatori, Zachary T Ball
Published: 202510.1002/anie.202523879
Abstract
Post-translational modifications (PTMs) play essential roles in living systems. However, the biological roles of some PTMs, such as N-terminal pyroglutamate, are poorly understood due to a dearth of chemical and/or biological tools to label, quantify…
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