Angewandte Chemie (International ed. in English)
Enhanced-mRNA Delivery Using Ultrasound-Delivered Anchors for Bioorthogonal Ligation.
Emilio Di Ianni, Jueun Jeon, Sedra Mohammadi, Huiyu Hu, Jeremy M Quintana, Chanseo Lee, Edwina Abou Haidar, Marie Goemans, Ayrton Zargani-Piccardi, Mohammed Mahamdeh, Iván Coto Hernández, Victoria E Rodriguez, Yirong Zhou, Aaron Aguirre, Shiaulou Yuan
Published: 202610.1002/anie.202523437
Abstract
Therapeutic nucleic acid delivery has many potential applications, but it remains challenging to target extrahepatic tissues in a flexible and image-guided manner. To address this issue, we report a bioorthogonal pre-targeting strategy that uses focu…
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