Angewandte Chemie (International ed. in English)HumansGlycosylphosphatidylinositolsMetabolic EngineeringCoculture TechniquesProtein Transport
Investigation of Intercellular Trafficking of Global Glycosylphosphatidylinositol-Anchored Proteins Using Cell Metabolic Engineering and Transwell Coculture.
Sayan Kundu, Zachary Bennett, Jiatong Guo, Palak Gupta, Zhongwu Guo
Published: 202610.1002/anie.202522420
Abstract
Glycosylphosphatidylinositols (GPIs) are essential for GPI-anchored proteins (GPI-APs), as the loose association of GPIs with the cell membrane is thought to facilitate GPI-AP shedding and intercellular trafficking, which dictates cell communication.…
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