Angewandte Chemie (International ed. in English)RubredoxinsPyrococcus furiosusMolecular Dynamics SimulationHot TemperatureCrystallography
Some Like It Hot -Structural Changes in Extremophile Rubredoxin at 120 °C.
Tzanko Doukov, Igor Leontyev, Francis E Jenney, Dominic George, Stephen P Cramer
Published: 202610.1002/anie.202520302
Abstract
How does the structure of a protein change as the temperature is raised from cryogenic conditions at 100 K to 393 K? Understanding the structure and dynamics of proteins under environmental extremes is relevant for human health, biotechnological appl…
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