Angewandte Chemie (International ed. in English)Alkyl and Aryl TransferasesModelsMolecularDiterpenesMolecular Structure
Structure Model-Guided Reprogramming Enables Functional Interconversion of Phomactatriene and Verticillene Synthases.
Li Zhang, Yinghan Chen, Yan Wang, Ao Zhu, Yi Ling Hu, Xiao Ling Huang, Qi Zhang, Yong Liang, Jing Shi, Hui Ming Ge
Published: 202510.1002/anie.202518926
Abstract
Terpenoids represent the most structurally diverse class of natural products on Earth. Terpene synthases are key enzymes for constructing the complex and varied terpene skeletons by catalyzing the formation of multiple carbon-carbon bonds. Phomactatr…
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