Angewandte Chemie (International ed. in English)
Palladium-Catalyzed Enantioselective Three-Component Dearomative Coupling of Bromoarenes: Modular Construction of Terpenoid Scaffolds.
Xiantao Wu, Zhonghui Shen, Hengrui Zhou, He Huang, Yunqiang Li, Jianrong Steve Zhou, Cheng-Yong Su, Zhiwei Jiao
Published: 202510.1002/anie.202518452
Abstract
We report a palladium-catalyzed asymmetric three-component coupling of bromoarenes, diazoalkanes, and malonates. It represents a significant advancement in catalytic enantioselective dearomative 1,4-difunctionalization of unactivated arenes. A pallad…
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