Angewandte Chemie (International ed. in English)HumansArginineProteomeCell LineTumor
Quantitative Reactivity Profiling of Functional Arginine Residues in Human Cancer Cell Line Proteomes.
Wenbo Zhao, Yuliang Tang, Yihui Gao, Qi Ding, Qiang Li, Wenyang Li, Xiaoguang Lei
Published: 202510.1002/anie.202515603
Abstract
Arginine, a critical amino acid for protein structure and function, is involved in enzyme catalysis and macromolecular interactions. However, selectively targeting its reactive guanidine group has been challenging. Here, we utilized a probe, AP-1, ba…
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