Angewandte Chemie (International ed. in English)OximesAldehydesHumansPhospholipidsFluorescent Dyes
Targeted Detection of Phospholipid Aldehydes in Living Cells by Oxime Ligation.
Jacob A Vance, Wei-An Chen, Palina Nepachalovich, Caroline Knittel, Maria Fedorova, Neal K Devaraj
Published: 202510.1002/anie.202512578
Abstract
Oxidatively damaged lipids play critical roles in numerous human pathologies, yet methods to directly identify these species within living cells remain limited due to their transient and low-abundance nature. Among lipid oxidation products, aldehyde-…
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