Annals of neurology
Non-Synaptic Function and Localization of Syntaxin-Binding Protein 1 in a Mouse Model of STXBP1-Related Epileptic Encephalopathy.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar, Alexey I Nesvizhskii, Michael D Uhler, Jack M Parent, Yu Wang
Published: 202610.1002/ana.78097
Abstract
OBJECTIVE: De novo mutations in the syntaxin-binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.…
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