Animal models and experimental medicine
The OtR tumor recurrence and metastasis model reveals doxorubicin-induced tumor shrinkage doesn't guarantee prolonged survival.
Lingli Luo, Ling Liu, Minyao Deng, Yong Jiang, Chuan Liu, Xiang Chen, Xiaoxi Li
Published: 202610.1002/ame2.70127
Abstract
BACKGROUND: In preclinical research, tumor growth inhibition in subcutaneous models is frequently employed to evaluate therapeutic efficacy; however, such models often lack clinical translatability. METHODS: To better approximate clinical reality, ta…
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