Animal models and experimental medicine
Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability.
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li
Published: 202510.1002/ame2.70090
Abstract
BACKGROUND: In recent decades, the global incidence of dengue fever has been steadily increasing, with continuous geographical expansion. Researchers have successfully modeled most clinical symptoms of human dengue fever using interferon type I (IFN-…
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