American journal of hematologyHumansHematologic NeoplasmsImmunotherapyAdoptiveReceptors
Strategies to Enhance CAR-T Cell Persistence in Hematologic Malignancies: From Molecular Design to Clinical Optimization.
Mengqi Yu, Tingting Yang, Shuyi Ding, Yongxian Hu
Published: 202610.1002/ajh.70131
Abstract
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated remarkable clinical efficacy in treating hematological malignancies. Nevertheless, the limited persistence of CAR-T cells in vivo remains a major therapeutic hurdle, leading to disease…
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