Advanced science (Weinheim, Baden-Wurttemberg, Germany)
MARPLE: A Proximity-Triggered CRISPR-Cas13 Platform for Ultrasensitive Antibody Detection.
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro-Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci
Published: 202510.1002/advs.202517799
Abstract
Monitoring clinically relevant antibodies-as biomarkers of disease or therapeutic response-is essential for informed clinical decision-making. Traditional immunoassays like ELISA offer reliable quantification but often involve multistep workflows and…
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