Advanced science (Weinheim, Baden-Wurttemberg, Germany)
HIDF: Integrating Tree-Structured scRNA-seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics.
Zhiyi Zou, Yuting Bai, Bo Wang, Wanwan Shi, Xiao Liang, Jiawei Luo
Published: 202510.1002/advs.202514073
Abstract
The limited spatial resolution of mainstream spatial transcriptomic technologies captures transcriptomic mixtures from multiple cells per spot, obscuring crucial single-cell information. While numerous methods leverage single-cell RNA sequencing refe…
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