Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Host-Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park
Published: 202610.1002/advs.202512972
Abstract
The increasing prevalence of emerging infectious diseases highlights the urgent need for broad-spectrum antiviral therapeutics. Here, the discovery of SB2960, a small molecule, is reported that promotes stress granule (SG) formation and exhibits pote…
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