Advanced science (Weinheim, Baden-Wurttemberg, Germany)Idiopathic Pulmonary FibrosisAnimalsNanoparticlesSignal TransductionMice
Pulmonary-Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy.
Xue-Na Li, Ya-Ping Lin, Xi-Xi Ma, Yue-Fei Fang, Hui Wang, Chun-Hui Cui, Chen Zhang, Jin-You Piao, Jee-Heon Jeong, Xian Wu Cheng, Lei Xing, Hu-Lin Jiang
Published: 202610.1002/advs.202512658
Abstract
Idiopathic pulmonary fibrosis (IPF) involves transforming growth factor-beta, a key factor that drives biochemical signaling pathways, inducing cellular transdifferentiation and excessive extracellular matrix (ECM) deposition. Increased ECM stiffness…
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