Advanced science (Weinheim, Baden-Wurttemberg, Germany)
METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation.
Shuang Li, Xiao Zhao, Tongtong Song, Qiaoyi Chen, Yanqing Wu, Yuting Zhang, Jingying Chen, Yifan Wu, Bin Li, Xinyue Zhang, Zihao Dai, Lixia Xu, Yubin Xie, Alfred Sze-Lok Cheng, Jianping Guo
Published: 202510.1002/advs.202512528
Abstract
The liver microenvironment is essential to immune surveillance and liver cancer progression. Here, the aim is to identify the role of METTL5, the 18S rRNA m6A methyltransferase, in regulating the liver immune microenvironment to promote cancer progre…
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