Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease.
Adriana N Santiago-Ruiz, Siewert Hugelier, Gabriela L Correa, Charles R Bond, Edward B Lee, Melike Lakadamyali
Published: 202510.1002/advs.202509773
Abstract
Tau aggregation plays a critical role in Alzheimer's Disease (AD), where neurofibrillary tangles (NFTs) are a pathological hallmark. While much attention is given to NFTs, emerging evidence highlights nano-sized tau oligomers as toxic entities. Using…
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