Advanced materials (Deerfield Beach, Fla.)
pH-Responsive Biomineralized Probiotic for Self-Amplifying Mucosal Vaccination: Gut-Engineered Antigen Factories Drive Targeted Cervical Tumor Regression.
Donglin Xia, Ziqing Gao, Jia Li, Chao Chen, Yan Xi, Siqi Li, Shuheng Qin, Xiqun Jiang, Minjie Chu, Yong Hu
Published: 202610.1002/adma.202510404
Abstract
Therapeutic vaccines against cervical cancer critically depend on sustained high-level HPV antigen production and prolonged antigen exposure. However, suboptimal antigen bioavailability and rapid systemic clearance remain key barriers to achieving ro…
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