Advanced materials (Deerfield Beach, Fla.)
Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform.
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J Rosenwasser, Iain E Dunlop, Derfogail Delcassian
Published: 202610.1002/adma.202505965
Abstract
Adoptive T cell therapies (ACT) are an important class of oncology treatments that require ex vivo T cell expansion for clinical success. Technologies that can control both phenotype and yield in expanded cell products are highly desired. Here, we de…
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