Advanced healthcare materials
Orchestrated Photothermal Nanoreactor Promoted Cuproptosis for Synergistic Cancer Therapy Through Glutathione Depletion and Gene Regulation.
Shujuan Cao, Fengqin Ding, Zhongkai Chen, Yanfei Cai, Jian Jin, Zhaoqi Yang
Published: 202610.1002/adhm.202505100
Abstract
Cuproptosis, a novel form of copper-dependent cell death, holds great promise for cancer therapy. However, the induction of cuproptosis is challenged by its reliance on copper ions and the high levels of glutathione (GSH) in the tumor microenvironmen…
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