Advanced healthcare materials
Highly Tunable and Cell-Remodelable Thiol-ene Alginate-Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication.
Julia Fernández-Pérez, Adrián Seijas-Gamardo, Antonio J Feliciano, Panagiota Kakni, Anna M Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B Baker, Lorenzo Moroni
Published: 202510.1002/adhm.202504313
Abstract
In this study, a cell-mediated degradable alginate hydrogel system for organoid culture and amenable to biofabrication technologies is presented. Norbornene-functionalized alginate is crosslinked with a di-thiolated peptide sequence cleavable by matr…
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