Advanced healthcare materials
A 3D Astrocyte Microenvironment Model Enables Rapid Ca2 +-Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation.
Ju-Kang Kim, Ye-Ji Kim, Seyoung Ryu, Daeui Park, Kyoung-Sik Moon, Yu Bin Lee, Dong Ho Woo
Published: 202610.1002/adhm.202504129
Abstract
Astrocytes orchestrate key neuroinflammatory processes, yet conventional two dimentional (2D) cultures distort Ca2+signaling and elevate inflammatory noise. Here, we introduce the Astrocytic Reactive-Calcium 3D microenvironment (ARC-3D), a tunable me…
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