Advanced healthcare materials
Targeted GPX4 Degradation Mediated by Hypoxia-Overcoming Nano-PDTACs for Synergistic Ferroptosis-Immunotherapy.
Rui Ji, Jiasha Wu, Luyi Wang, Fusheng Xu, Jiwen Hu, Yejiao Shi, Siyao Liu, Feng Xu, Xiaochun Hu, Honggang Hu
Published: 202510.1002/adhm.202503869
Abstract
For triple-negative breast cancer (TNBC), ferroptosis is a promising therapeutic strategy, with photodynamic therapy (PDT) being an effective method to induce it. However, PDT-induced ferroptosis has limitations such as poor tumor targeting, unclear…
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