Optimized TPL6 Peptide Gel Exhibits Broad-Spectrum Antimicrobial Activity and Effectively Treats Drug-Resistant Wound Infections in Diabetic Mice.

Antibiotics are the primary treatments for diabetic foot infections (DFIs) but are often ineffective against severe, polymicrobial, or drug-resistant microbial strains. Antimicrobial peptides (AMPs) offer broad-spectrum activity, yet most fail in cli…

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