Advanced biologyTumor MicroenvironmentAnimalsLung NeoplasmsMiceAdenocarcinoma of Lung
A tumor Microenvironment-Derived Prognostic Model Guides IL-27 as a Therapeutic Strategy to Restore T Cell Immunity in Lung Adenocarcinoma.
Gaopu Xie, Donglin Cai, Gang Zhang, Hongda Zhao, Xu Wang, Li Zhu, Jing Ni, Xia Yi, Jun Liang, Mengmeng Liang
Published: 202610.1002/adbi.202500547
Abstract
Lung adenocarcinoma (LUAD) exhibits substantial heterogeneity in tumor immune microenvironment (TIME) composition, shaping disease progression and therapeutic response. Here, we integrated transcriptomic and clinical data from TCGA-LUAD to develop a…
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