Molecular oncology
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D Garg
Published: 202610.1002/1878-0261.70210
Abstract
Triggering receptor expressed on myeloid cells 2 (TREM2) has emerged as a key immunosuppressive target on tumour-associated macrophages (TAMs), where it coordinates protumorigenic and anti-inflammatory functions within the tumour microenvironment (TM…
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