Molecular oncology
TREX1, a predator for treating MSI-H tumors?
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde
Published: 202510.1002/1878-0261.70173
Abstract
Immunotherapy has revolutionized cancer treatment; yet, a subset of patients with microsatellite instability-high (MSI-H) tumors fails to respond to treatment despite their elevated tumor mutational burden and immunogenic potential. In a recent study…
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